Gynecomastia, or the enlargement of breast tissue in men, is a condition that affects many and can be a source of concern, discomfort, or even embarrassment. While there are various reasons why gynecomastia may occur, one common but often overlooked cause is medication.

If you’re wondering whether your medications could be contributing to the development of gynecomastia, you’re not alone. At the Las Vegas Gynecomastia Center, Dr. Frank Stile and our dedicated team are here to help guide you through understanding this condition and how to address it.

Let’s dive into how certain drugs may trigger gynecomastia and what steps you can take to move forward.

What is Gynecomastia, and How Do Drugs Play a Role?

Gynecomastia occurs when the tissue around the breast becomes enlarged due to an imbalance in hormones. In most cases, an excess of estrogen relative to testosterone is the culprit. Many medications have the potential to interfere with your body’s natural hormone levels, leading to this condition.

The good news is that in many cases, adjustments in your medication or alternative treatments can reduce or even reverse the symptoms. So, if you’re taking medication and notice changes in your chest area, it’s important to consult with a medical professional who can help you determine the best course of action.

Common Medications Known to Cause Gynecomastia

1. Anti-Androgens and Hormonal Treatments

Anti-androgens, used primarily to treat conditions like prostate cancer, are well-known to cause gynecomastia. These drugs block testosterone, which can lead to an increase in estrogen levels.

Some commonly prescribed anti-androgens include bicalutamide (Casodex) and finasteride (Propecia, Proscar), the latter being used for hair loss and benign prostatic hyperplasia (BPH). The hormonal shift that these drugs create can lead to breast tissue enlargement.

2. Anabolic Steroids

Anabolic steroids, often used by athletes or bodybuilders to enhance muscle growth, can also lead to gynecomastia. When anabolic steroids are introduced into the body, they may convert into estrogen, leading to an imbalance between estrogen and testosterone. This hormonal imbalance is a significant trigger for the development of breast tissue in men.

3. Medications for Heart and Blood Pressure Conditions

Drugs like spironolactone (Aldactone), a diuretic used to treat heart failure or high blood pressure, are also associated with gynecomastia. Spironolactone blocks testosterone, which can lead to a relative increase in estrogen. Similarly, calcium channel blockers and certain ACE inhibitors may also contribute to this condition.

4. Antidepressants and Antipsychotics

Some mental health medications, including tricyclic antidepressants and antipsychotic drugs, have been linked to gynecomastia. For example, risperidone (Risperdal), commonly prescribed for schizophrenia or bipolar disorder, may increase prolactin levels, a hormone that can promote breast tissue growth.

5. Anti-Ulcer Medications

Drugs like cimetidine (Tagamet), used to treat peptic ulcers or gastroesophageal reflux disease (GERD), have also been known to cause gynecomastia. Cimetidine is a histamine H2-receptor antagonist, and long-term use can lead to elevated estrogen levels.

Gynecomastia Causing Drugs

What Should You Do If Your Medication is Causing Gynecomastia?

If you suspect that your medication is causing gynecomastia, the first step is to consult your doctor. It’s crucial not to stop or adjust your medication without professional guidance, as this could cause other health complications.

Dr. Frank Stile at the Las Vegas Gynecomastia Center recommends working closely with your prescribing doctor to explore alternatives. In many cases, switching medications or adjusting the dosage can alleviate the symptoms.

If your medication is essential for your overall health and alternatives aren’t available, we can help you explore other treatment options for gynecomastia.

Are There Non-Surgical Treatments for Drug-Induced Gynecomastia?

If your medication is causing mild gynecomastia, your symptoms may resolve on their own if the medication is stopped or changed. However, in some cases, the breast tissue enlargement can persist. Here are some non-surgical treatments that may help:

  • Watchful Waiting: If gynecomastia is mild and doesn’t cause physical discomfort or emotional distress, your doctor may recommend monitoring the condition without immediate intervention.
  • Medications: Some drugs, such as selective estrogen receptor modulators (SERMs), like tamoxifen, may help reduce breast tissue in men.
  • Lifestyle Changes: Maintaining a healthy weight and avoiding substances that could exacerbate gynecomastia, such as alcohol or recreational drugs, can also help manage symptoms.

When is Surgery the Right Option?

For some men, drug-induced gynecomastia can be persistent and more than just a cosmetic issue. It can lead to physical discomfort and emotional distress. If this is the case for you, surgery may be the best option.

At the Las Vegas Gynecomastia Center, Dr. Frank Stile specializes in minimally invasive gynecomastia surgery to help restore a more masculine chest contour.

Surgery is typically considered if:

  • You’ve experienced gynecomastia for more than a year, and it’s not improving.
  • The condition causes discomfort, tenderness, or emotional distress.
  • Non-surgical treatments haven’t provided sufficient relief.

During a consultation, we will explore all options that are right for you. We will also discuss pre-op preparation and post-op recovery tips like when you can return to the gym after surgery.

Gynecomastia Patient Before and After Stage 1

Taking the Next Step

Gynecomastia caused by medication can be a challenging condition to navigate, but it’s important to know you have options. Whether you’re looking for a change in medication or considering surgery, Dr. Frank Stile and our team at the Las Vegas Gynecomastia Center are here to help you every step of the way.

We encourage you to schedule a consultation if you’re concerned about gynecomastia. Let’s work together to find the solution that’s best for you and help you regain confidence in your body.

If you’re ready to take the next step or have more questions about gynecomastia, feel free to contact us at the Las Vegas Gynecomastia Center.

Dr. Stile and our experienced team are here to guide you through this journey with personalized care and professional expertise.


At the Las Vegas Gynecomastia Center, we prioritize delivering exceptional care from your initial consultation to your recovery and beyond. We deeply value the trust you place in us and are committed to upholding the highest standards of patient care. Our team, led by board-certified gynecomastia plastic surgeon, Dr. Frank Stile, is devoted to achieving optimal outcomes for each individual. Recognizing that every person is unique, we personalize our approach to meet your specific needs. Whether you have questions or are ready to schedule your in-person or virtual consultation, please don’t hesitate to contact us today. We’re here to support you every step of the way!

Las Vegas Gynecomastia Center
8954 Spanish Ridge Ave #1A
Las Vegas, NV 89148
(702) 710-4270